Biology
AlphaFold 2
Predicting protein shapes
Google
What do you need AI to do?
Type the job. We show which AI tools really do it, what they cost and which one we would pick.
Front desk
The Best AI Answering Service for Home Service Businesses
When you are on a roof or under a sink, the phone goes to voicemail and the job goes to the next contractor. An AI answering service can pick up, book the visit and flag the emergencies. Here is the one we would try first.
Our pickRosie
Front desk
The Best AI Booking Assistant for Salons
Your phone rings mid color, mid cut, mid blowout. An AI booking assistant can answer, book the client into an open slot and take the deposit. Here is the one we would try first.
Our pickGlossGenius Reception
Finance
The Best AI Bookkeeping Software for Small Businesses
AI can now sort most of your transactions, match them to your bank and remind late payers for you. Here is the software we would start with, a cheaper option, a free one, and when it pays to go further.
Our pickQuickBooks Online
Chatbots
The Best AI Chatbot
One AI assistant can now draft your emails, read your contracts, research a supplier and make a quick image for a post. Here is the one we would pay for first, the best free option, and when to spend more.
Our pickChatGPT
Chatbots
The Best AI Chatbot for Small Business Websites
A good AI chatbot answers the same 20 questions your staff answer every day, at any hour, and passes the rest to you. Here is the one we would install first.
Our pickTidio
Coding
The Best AI Coding Assistant
AI coding tools can now fix bugs, write tests and build features while you review the work. Here is the one we would start with, the cheapest good option, and the best free one.
Our pickClaude Code
Know when AI breakthroughs become real.
Most AI news stops at the announcement. We follow each breakthrough from claim to real use, in plain English, with the sources.
Widely used in real work beyond the team that built it.
You can try it: public code, a model, a tool or a dataset is available.
Biology
AlphaGenome Atlas
A map of predicted DNA variant effects
Google
Biology
AlphaGenome
Predicting the effects of DNA changes
Google
Computing
AlphaEvolve
Algorithms that improve through automated tests
Google
Biology
AlphaFold 3
Predicting how biological molecules fit together
Google
Mathematics
AlphaGeometry
Solving Olympiad geometry
Google
Climate
GraphCast
Fast global weather forecasts
Google
Checked by outside experts, official judges or by results anyone can recheck.
Mathematics
Gemini Deep Think at IMO
Gold medal standard in mathematics
Google
Mathematics
AlphaProof and AlphaGeometry 2
Silver medal standard on IMO problems
Google
Mathematics
FunSearch
New mathematical constructions from code
Google
Computing
AlphaTensor
AI finds new matrix multiplication algorithms
Google
Announced or reported by the team behind it. Not yet checked by others.
Mathematics
OpenAI mathematics collection
722 manuscripts. A new scale of AI mathematics.
OpenAI
Biology
Claude’s ART enzyme system discovery
Claude spots a hidden pattern in DNA: the ART enzyme system
Anthropic
Computing
AlphaEvolve in practical systems
Algorithm discovery reaches more applications
Google
Mathematics
OpenAI First Proof submissions
Proof attempts on research mathematics
OpenAI
Physics
GPT-5.2 and gluon amplitudes
A new formula in particle theory
OpenAI
Science
GPT-5 science case studies
AI contributing to research with experts
OpenAI
Biology
AI co-scientist
Generating hypotheses for scientists to test
Google
Materials
GNoME materials research
Searching for stable new materials
Google
Follow a breakthrough and we’ll tell you when it moves. How we decide each stage
Latest from the field.
A NEW POSSIBILITY Oct 6, 2026
AI is tackling
unsolved math problems.
A glimpse of AI doing original research: 722 math manuscripts from OpenAI. Some results have been checked; others still need review.
What happened & why it matters Some results still need checking
EARLY RESEARCH
AI finds a new clue in DNA.
An enzyme discovery opens a research question. It does not yet establish a treatment.
Anthropic · Sep 23, 2026RESEARCH RESOURCE
Exploring what changes in our DNA could mean.
A map of predicted DNA changes, with clear limits on what predictions tell us.
Google · Sep 8, 2026THE LONGER VIEW
Remember what AI used to be like?
See the progress from earlier models to today. Tap a dot to meet the model.
Open the interactive chartOpenAIAnthropicGoogle
Best model scores by company · Source: Epoch AIKeep exploring
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The Best AI Answering Service for Home Service Businesses
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Oct 9, 2026Buying guide
The Best AI Booking Assistant for Salons
Your phone rings mid color, mid cut, mid blowout. An AI booking assistant can answer, book the client into an open slot and take the deposit. Here is the one we would try first.
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The Best AI Bookkeeping Software for Small Businesses
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The Best AI Chatbot
One AI assistant can now draft your emails, read your contracts, research a supplier and make a quick image for a post. Here is the one we would pay for first, the best free option, and when to spend more.
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The Best AI Chatbot for Small Business Websites
A good AI chatbot answers the same 20 questions your staff answer every day, at any hour, and passes the rest to you. Here is the one we would install first.
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The Best AI Coding Assistant
AI coding tools can now fix bugs, write tests and build features while you review the work. Here is the one we would start with, the cheapest good option, and the best free one.
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The Best AI Email Marketing Tools for Small Businesses
AI can now draft your newsletter, suggest subject lines and send each email when a customer is most likely to open it. Here is the tool we would start with, and the best free plan.
Oct 9, 2026Buying guide
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